Exhibit 99.1

Selecta Biosciences Announces Second Quarter 2018
Financial Results and Provides Corporate Update

Expanded three-month Phase 2 data presented at EULAR 2018 continue to indicate that SEL-212 product profile may provide better and more sustained serum uric acid control, fewer flares and less frequent dosing compared with data reported for current FDA-approved uricase therapy
Data from patients receiving five monthly doses of SEL-212 expected to be presented at the American College of Rheumatology (ACR) Annual Meeting in October 2018
SEL-212 Phase 3 pivotal program expected to begin in Q4 2018 with a planned head-to-head trial against Krystexxa conducted in parallel
Enrollment ongoing for SEL-403 Phase 1 trial for mesothelioma, company working with NCI to potentially expand clinical studies for treatment in pancreatic cancer
Company to host conference call today at 8:30 a.m. ET

Watertown, Mass., Aug. 8, 2018
- Selecta Biosciences, Inc. (Nasdaq: SELB), a clinical-stage biopharmaceutical company focused on unlocking the full potential of biologic therapies by mitigating unwanted immune responses, today reported financial results for the second quarter ended June 30, 2018 and provided a corporate update.

“The continued improvement in clinical activity observed in the expanded patient data set recently presented at the EULAR conference in June further demonstrates the benefit SEL-212 may provide to chronic severe gout patients and its potential ability to change the current treatment paradigm in these patients with high medical need,” said Werner Cautreels, Ph.D., President and CEO of Selecta. “We look forward to presenting data from patients receiving five monthly doses of SEL-212 at the upcoming ACR meeting in October and expect to initiate the Phase 3 program for SEL-212 in the fourth quarter of this year. In addition, we plan to conduct a head-to-head clinical trial against Krystexxa in parallel with our Phase 3 program."

Recent Highlights and Anticipated Upcoming Milestones

Presented New Expansion Data from Ongoing Phase 2 Trial of SEL-212 at the European League Against Rheumatism (EULAR) 2018 in June: In June 2018, Selecta presented new expansion data from patients receiving SEL-212 for the treatment of chronic severe gout at EULAR 2018 in Amsterdam, the Netherlands. The data was from patients receiving three monthly doses of SEL-212, up to 0.15 mg/kg of SVP-Rapamycin in combination with 0.2 or 0.4 mg/kg of pegsiticase, followed by two monthly doses of pegsiticase alone. Approximately 80% of evaluable patients (n=27) had serum uric acid control below 6 mg/dl at week 12. In a separately conducted and designed study of the only FDA-approved uricase therapy, 44% of evaluable


The following information was filed by Selecta Biosciences Inc (SELB) on Wednesday, August 8, 2018 as an 8K 2.02 statement, which is an earnings press release pertaining to results of operations and financial condition. It may be helpful to assess the quality of management by comparing the information in the press release to the information in the accompanying 10-Q Quarterly Report statement of earnings and operation as management may choose to highlight particular information in the press release.

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