Exhibit 99.1



Investor Contact:
Kurt Gustafson
Halozyme Therapeutics
858-704-8272
ir@halozyme.com

Media Contact:
Nurha Hindi
Hill + Knowlton Strategies
310-633-9434
Nurha.Hindi@hkstrategies.com

Halozyme Reports Fourth Quarter and Year End 2012 Financial Results

SAN DIEGO, February 25, 2013 -- Halozyme Therapeutics, Inc. (NASDAQ: HALO) today reported financial results for the fourth quarter and year ended December 31, 2012.

"2012 was another productive year marked by key partner regulatory filings in Europe, as well as our establishment of a new collaboration with Pfizer," said Gregory I. Frost, Ph.D., President and Chief Executive Officer, Halozyme. "These advancements, coupled with the continued progress of our own pipeline products, leave Halozyme well-positioned for continued growth in 2013.”

Fourth Quarter Highlights 
Highlights of Halozyme's fourth quarter and recent activities include:

Pfizer Collaboration: Entry into a worldwide Collaboration and License Agreement with Pfizer Inc. for the purpose of developing and commercializing products combining proprietary Pfizer biologics with Halozyme's Enhanze™ Technology. Pfizer has elected three exclusive licenses to therapeutic targets in primary care and specialty care indications, and has the right to elect up to three additional targets upon payment of additional fees.
 
Cinryze® Phase 2 Trial: ViroPharma initiated a Phase 2b study to evaluate the safety and efficacy of subcutaneous (SC) administration of Cinryze (C1 esterase inhibitor [human]) in adolescents and adults with hereditary angioedema (HAE) for prevention of HAE attacks.



The following information was filed by Halozyme Therapeutics Inc (HALO) on Monday, February 25, 2013 as an 8K 2.02 statement, which is an earnings press release pertaining to results of operations and financial condition. It may be helpful to assess the quality of management by comparing the information in the press release to the information in the accompanying 10-K Annual Report statement of earnings and operation as management may choose to highlight particular information in the press release.

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