Exhibit 99.1
Jim Mazzola

Chris Burton



- Strong progress in global HALO 301 clinical trial following positive randomized Phase 2 HALO- 202 results -

- Supportive partner data presented at ASH in two key ENHANZEplatform programs -

- 2016 Royalty Revenue of $51 million increased 65 percent from prior year -

SAN DIEGO, February 28, 2017 - Halozyme Therapeutics, Inc. (NASDAQ: HALO), a biotechnology company developing novel oncology and drug-delivery therapies, today reported financial results and recent highlights for the fourth quarter and full year ended December 31, 2016.

“We exited 2016 in a strong position through the benefit of our differentiated business model and having made substantial progress across both of our value-creating pillars,” said Dr. Helen Torley, president and chief executive officer. “The positive Phase 2 data we reported last month affirms our conviction in PEGPH20, our lead investigational oncology drug, and supports our ongoing Phase 3 study in pancreas cancer patients. We have made strong progress initiating global sites in the Phase 3 study and see momentum building in the number of patients we are screening.

“Our ENHANZE™ platform remains an important value driver as royalty revenue demonstrated yet another quarter of robust growth, and exceeded $50 million for the year. With positive data presented by Genentech and Janssen at the American Society of Hematology annual meeting for their ENHANZE-partnered programs and a recent BLA filing in the U.S. by Genentech, we remain very encouraged by the royalty growth potential from current and new products over the long term.”

The following information was filed by Halozyme Therapeutics Inc (HALO) on Tuesday, February 28, 2017 as an 8K 2.02 statement, which is an earnings press release pertaining to results of operations and financial condition. It may be helpful to assess the quality of management by comparing the information in the press release to the information in the accompanying 10-K Annual Report statement of earnings and operation as management may choose to highlight particular information in the press release.

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